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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8e5a24823436cc4424d4adf0feb60ab93697b4d82a80e150cb4c6319501400' 
  AND token = 'szKml/lZozCUzvpewQu8ZYPdDx6FHskzhzPmZpz6RZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}