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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805ade278d3f690e8d08d6a37c62136a8698c90350e3ba7ea05dec5d92b40cfd' 
  AND token = 'qNwoVH47zJH+45JSltOstU5qczvcFmyC9HK0SVpF39k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}