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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a17941b824c717d6431449321aacd12d8f8ff680c4fe4939b6fca098e382586' 
  AND token = 'WI9scU57RQP5MVQW0w2eRzPuTuz0MvQNY8pzJKnn9Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}