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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9975f5b4f9ee88526c1a9d5bdede4f0f536d9f8f59d197474344e871c36b4326' 
  AND token = 'vNr6TDo8UHTxe7/Par35OLSYTNmvX8eRJ/UO0i8n4kE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}