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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bce0b45484957dea5b44a4c17a2a9960aa281b747851660a64d20264c6e89f6' 
  AND token = 'Yxm+8kHsJZzhB4+BIS/IQ8sVyEEMo/N8UMWTTlUB2qU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}