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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '322d47ae2f064256f680c7c9ab18292eb6ec42f242d5ee936465184bde5ae978' 
  AND token = 'B69T9RDOX1fdpN8fDsdBC0fCG+3nQ2LswEzL7zxCI6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}