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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4202ae8fe7493145f1f29b64cb29de4ad41aff711218baace457a7da68f6a3b7' 
  AND token = 'alz9xLvVcdH/VS7p5kzc3W2FfIFtp9jNLoiwWg+l5XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}