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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76916e7dc751e8c1a28fc4d2ca98e18554595c0073d4fd3e954e024af9d62185' 
  AND token = 'DiixCfL1bp/6ClVk1Tn9MbbTIghuSMe5UpYDc7GJheI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}