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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '558dcf98c1112096eed2fa9738e17cdc6740a80ac17752c96b0075d200dd7b08' 
  AND token = 'KE/qPDIbF30QejDZVDa70OQC4K2Gdz9xZqejtq7wRD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}