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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efc497cc028c54838711f2898a3d48f61aa4f24c45b88d6159587c10590b33a5' 
  AND token = 'N4KZ8W0ONQNNqczE43TtYKhZb9MmgAxmTGKOmVTqhdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}