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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0dbf15ab5dd42451c7274b2b690b0854c32580e2ee6fae453a5c16938c3e745' 
  AND token = 'Wk42HdaA/G2VZ27K2qdwZ7UMjFARrlC89DI+lTSNeWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}