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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b69d28f744f3bf61ede42e75daf78f14a521d1eae2241cafa626b9fa51bd9770' 
  AND token = '0yVwPlPwOZaRGhhG7PW9A1bxWrLBnQqhAxTiZTAlvt0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}