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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45597166955b47d0696e495b67cf1c032ccb4a1b5a5b9ddc5c35e31ac2c15ad5' 
  AND token = 'ttdJGZUojZe1vNTEHIVx623X/+IDvA/9qPC+Ez3VW8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}