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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f982451719d6d617459422b16742247a2de8f512ea44d76409023213dc77210' 
  AND token = 'cwspLb/pX/TmRB7Y3iTRGPKGtzy5t5MHUB3IfU5S2mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}