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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5186e99559f1cbb46659fb4191130de952e93f2fdb540e7506af3e5073d698e7' 
  AND token = 'd3m19Sr8kjIvtrZxCBj5GmjyF4cjQWpumDhi1xWT4fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}