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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2665e5fec77272c75eab949a620746151fb870a55c050ae3d98a038849253b' 
  AND token = 'cmvCaN8qHQGwUgelItkUr0Q8A2OM7BxtLsTXiLLMWXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}