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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8cc49114afcf90879ea6590ce8e936efc68e80ce99fa979ebfa412d9adbb7f' 
  AND token = 'p0mQ0SSHs/uYHzk8CNGm6PnsdUn+QAkgbtkmuTPCMSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}