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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7e963afc5e65dce9d4914f844a884b242009916d6cfd907f8784d69a5d2e22c' 
  AND token = 'CpltZcUFm+BYYiCPH/l3ewdXzDRZe5gm4T1imHaJ+lM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}