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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7516614423c170e158a32d0ac2b900d37e9252848f08b0bcb1178d711c4d24da' 
  AND token = 'GbbYWtnYpIhb4S1omNF4BRpYE0enOwggR9CplYer6j8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}