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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1325d8f51dabfcd87bf9caba6c54cc29fa091d6b12d1aff401e0bf461a2595d3' 
  AND token = 'RE2Mqh84aXyIqK/zWabfHJGtEcZRGN2dXHF8rOhqKQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}