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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9fe18f51211955c777a66d1a0929bbd5ad783c90b330eea0ec74b163a7e1873' 
  AND token = 'EDvk2C9Zz2i/w9pa8X35vxRXB9XYV53Ewmhb+HYzs90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}