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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df36789764536061d27dc7b2599d1b672c45dd30fdc629797aecd0426f42e0c' 
  AND token = '/fkRt9C5IzQ1qTkOgX1nn8mBRWRzSCjjOHNvuD+poo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}