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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d9f071a6bbcdda172ed46480fd32c1bf05d9210900a557213a2f4c94c095440' 
  AND token = 'o2PLX6rp89xotVGVDF2g/bIcFFKZrqQB/xx2bRjUiBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}