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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8b5fd56498f630ce8e513d2183a0f26e8c77466de11b927da2159f1b68413e' 
  AND token = 'zC1IzcLBsyfWERnx+cVG9WswzS7x+w7dk8/74bpxz8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}