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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e433a5a6edb1ca435ce7359671cbff0c9fd90c2d2d81c0141057a8cf23314a9' 
  AND token = 'RkUQ76LqR+6oUEZXE5mlUKi2FhFElNgd2H+Tp6LGVEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}