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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e5a735f0f1e90d378f3569c2e91a1d8250cc3816e5166683d159ef29ea5aa0' 
  AND token = 'F7yfV9kLVUlIc5WKi/nrJLIHxIubJzyUhF4tpbXBYxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}