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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d9e42cff140143dc4691c55523f31ad1237fb2f969cf007e02ab00a74d0fac' 
  AND token = 'wK9Nce8esmt+2S3FTZUGj9LbpOnvxpR3FLUd2FaUQHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}