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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ed2be6372fb048f7aaefe3b8669d5e8f91d5c74fbc90a2ab7e4d89de87bb6f' 
  AND token = '8zmSk09lCYFO8IpVGsYlZnbZ/pdk7yPVZCAEwziDiPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}