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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0775de9926197b9d6010babd2c48548d5e8a8ce1d66b088bebf1b067d10b281b' 
  AND token = 'ILtNWgDcDzjeI0LQ65Hu8kjPWk99SmxBjRDXs5Cp9PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}