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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c28ddb48202e777949112bceb6bd70deb60f7c8ed799fd67dadd7afae9e51350' 
  AND token = 'FsdxDycLZcy8wOgjXuUBgf9awsBLGab5xWEK6AxKVQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}