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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '373515d20743a23499375d9a5009f3ff84a33d29ee052e0f8b3d5ea387d2e602' 
  AND token = 'JWu6Yx02kHbpiITJ2gvgFW4zdUwingZnyPfvgpwuSJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}