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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c0c8687b797b6c58bf199db139f8ab6b9d5fecd272738525da1e9c0841143b1' 
  AND token = 'Af5KB4gN6tZswLQOf/cwjTaePPOpKxAR1R7dYWiwS7o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}