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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b0266ea58e8766cbb2b7568aaf473fe71c637e2d16477241ee807d9e5b2e2c7' 
  AND token = 'rlGqhzi5y64TDAJ4ZaX21OrLlVmkqGGP2zayWvb0BJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}