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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5b3011f57d6d816b055bec101ffb499853153bf6036c404ed0f2ea4be21c0e6' 
  AND token = 'X9+5CKtivOIyWANrxQCDodQoaIzNyk4QUw4xQ1D1cm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}