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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d27602b5c899c0931fb159c1e0cec275309e11353989355161cae1d5f8800a' 
  AND token = 'j3c18YtU+xbrjCQYF5IThpG3VHPxD6n2jpTTGNrU03Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}