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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5021a8e4e00312d9d0b5c19cb56e087183f7b22d68149b22b7c3788f0a6c3561' 
  AND token = 'XYmV+5i2s80SlETv1PG67oURFe5EjGSIjJKXCBNLldw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}