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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71e504b4b856dc2e2096ec245fc13d109f69ff580050c436b08a4136a4d20188' 
  AND token = 'eZ1Pe8DnVow/Ysvw0IDpCLQ3Im3T2UwuQZTaiJi2Tco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}