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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16d427da324d49c81279d52f8a8f4115fa1f02f7e4ad9320c328e8eb10dea2d2' 
  AND token = '7ZBC686paA0vjgXZqrOdvMRyuU2qYgHwWf6mkJvHf7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}