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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73439bf40ac731e330f4b19fa96183cdb8d5c3d2323bf1c5a84f9507d8381cb2' 
  AND token = 'kAEO7jdX9G3OImcnMIsMvK4Smw5h9bXJOpvROe9EQLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}