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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea1cf7ca01160037aa271a7b4b74e508e5638844d5270df6f2d0e4d7b494dd4f' 
  AND token = 'PZMLnK3kSmcl/+T7WasXCmZfZQV98e6AuB98PYfq5Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}