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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503ac2d8e7eb108639fc399f2a21ca6e61e3b1503ded1e2a4ab063ace28fb169' 
  AND token = 'nFMMhYmQy5gFzHEo0viSv+gfx2Db5SFpq21UKSF++Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}