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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5f74fe21b7240f6c3235ab09be9bb1bef4f266a8d04fccc88ae0038acc5f48' 
  AND token = 'Ql4lMXRd+ZwvPBpAKdK8WF7IO2vPCnYwm/P8Vtvo82A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}