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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df164318688944ef002e36f1f034c32ee5bbbb1ecb459c854f74a2a251b218a7' 
  AND token = 'uqHN5TicwSZoVxmAM0L7hpbl3zLHbcDE+7Ii0NSPl5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}