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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b208fb6ee786adb3c58303b872252a6265ace74c4e3aab3ce880b9319412df9' 
  AND token = 'lQ7eSxeL77XIFbDhkGYY3R6Tfq5RPEE2/doHHEdN94Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}