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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87ecde86cae60c329db6e9ea7cacde1e020169a1053d7c1ac09f8ead17b1d81c' 
  AND token = 'Ux3EE66vozkYOcQgTvp4c2OvLDLRW+fLxpNbU42vdDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}