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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8b729a2af3005ace04aa44f72d892c622d24c24c31e2b46636d727b940aeeed' 
  AND token = 'dTUhyu9G/m+aIbr+qSl6LO6x0pyj4VnapWAac9t+3ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}