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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6778e077c4654f466374d57b4c5372d457c2c6cb78fb06dd337ff99f45b113c0' 
  AND token = 'sDJcF6mTIoeJXCXQABKM7J4kXmxw5TYwS3ZPgugEaoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}