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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9632d36ef7860011523c4292a0d929184c6e68a4ac809ea9d8d9f8e8e19d58a' 
  AND token = 'fp+Mt4bIt881JufDZT5OSPPOXVHX9qFPUbhE1A0FrO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}