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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1c636791750a2a4f6e55f4e425f68046fd398dbc7a804727719d9e6f5c9e2c6' 
  AND token = 'yI5JfS9/53NhJpc7JQcSJrwa6bF/hYSmSkB/TcBsXcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}