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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28d009be6f2ac8cf1b4a12fc233476cd7a81215de753cb4a1cce225350b4ccc4' 
  AND token = 'BcYUBrkqmpuHNb3a/4Jw3jxl1MQnjvlWYHPACgiWETk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}